Multiple Spoofed HTTP Requests

[kuffya () gmail com]

Hi list, 
I've used a variety of tools such as Nemesis, Packet Xcalibur & Libnet GUI to craft customized packets. Using such 
tools, you can create packets at layers 2 up to 5 possibly spoofing your source IP, port numbers or whatever you see 
fit. 
The question is : Would it be possible to craft a HTTP request(or multiple requests) using a spoofed IP address? I'm 
inclined to consider that it's not, the reason being you must have a 3-way handshake established before you can start 
talking application layer protocols (such as HTTP). If you use a spoofed IP address, then there's no way of doing that. 
On the other hand, I might be totally wrong, that's why I'm asking the list, for the list is wise. 
If, however, it is possible could you please give me some directions on how to do it? 

Thanks a lot
S.

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