Interesting People mailing list archives

IP: drug-resistant infections...


From: David Farber <dave () farber net>
Date: Wed, 17 Oct 2001 23:11:33 -0400


To: dave () farber net
Subject: drug-resistant infections... (for IP)
Date: Wed, 17 Oct 2001 23:00:40 -0400
From: "Mike O'Dell" <mo () ccr org>

Dave,
if you'll permit a personal crusade item...

having fought a battle with an MRSA infection (methicillin-resistant
staph), i can tell you that *very* few things scare me more than the
alarming rate of increase in drug-resistant infections.  seeing a
9-year-old at the bug doc's for his PIC line maintenance is pretty
unsettling, but then discovering he didn't get the infection from
surgery, but that he got it from "just a cut i got out in the woods"
should concern *everyone* in a very direct and personal manner.

the most infuriating part of MRSA is that they know with almost
complete certainty how the drug resistance arose.  It seems that
farmed fish are fed high levels of methicillin-family anitibiotics and
the comfy aqueous envirnonment allowed the staph bacteria to develop
immunity thousands of times faster than would have happened in the
human population alone.

if you get a descendant of those staph bugs, like i did, there are
only a couple of drugs left to use.  they are extremely expensive,
only administered IV+PIC, often toxic, and the bugs are developing
resistance to those, too.

note that many of the most powerful antibiotics are *not* metabolized
in the body but simple excreted intact.  this means what happens in
the sewer pipes can be the same thing that happened in the fish ponds,
especially if lots of people are eliminating them at the same time.

people MUST take anti-biotic over-use very, very seriously.

they are miraculous drugs, but *only* if you really need the miracle.

        -Mike O'Dell


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