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DNA may tell police the surname of the criminal


From: Dave Farber <dave () farber net>
Date: Wed, 22 Feb 2006 09:22:01 -0500



-------- Original Message --------
Subject: DNA may tell police the surname of the criminal
Date: Wed, 22 Feb 2006 13:09:16 +0000
From: Brian Randell <Brian.Randell () newcastle ac uk>
To: dave () farber net

Hi Dave:

From today's (UK) Guardian:


How DNA may tell police the surname of the criminal

Alok Jha
Wednesday February 22, 2006
The Guardian

Police will soon be able to predict the surnames of criminals whose 
DNA is found at crime scenes, according to research published 
yesterday. The technique would only work in finding men, however, as 
it is based on identifying similarities in the Y chromosome, which 
is passed from father to son.

The technique relies on research carried out by University of 
Leicester scientists into how Y chromosomes have spread through the 
British population. They analysed these chromosomes in 150 pairs of 
men with the same surname and found that, in a quarter of cases, the 
pair had matching Y chromosomes.

When the most common names were excluded from the list - Smith, 
Jones, Williams and Taylor, for example - the chance that two men 
with the same surname shared a Y chromosome jumped to 50%. The 
research appears in the latest edition of Current Biology.

Mark Jobling, a geneticist at the University of Leicester who led 
the work, said the police would need a relatively small collection 
of male DNA - around 40,000 people - to allow useful matches to be 
made. "That sounds big but the national DNA database is nearly 100 
times bigger," he said. By matching the Y chromosome details of 
unidentified DNA at a crime scene with the database, police would 
get a list of potential surname matches.

"That would allow you to prioritise suspects in your investigation," 
said Dr Jobling. "If you have a lot of suspects - say a whole town 
or something - you can say we have 50 names, are these names 
represented here, if so let's go and interview these people."

Y chromosomes are passed from father to son mostly unaltered. Once 
in a while, they will acquire random mutations as they pass through 
the generations. Some parts of the chromosome are known to mutate 
less rapidly than others and, by mapping these differences, 
scientists can create a tree showing the relationships between 
different Y chromosomes.

"If men fall in different branches of the tree, there's no way they 
can be related to a recent male ancestor," said Dr Jobling. "If they 
lie within the same branch, there is a chance they are, but it 
doesn't prove it.

"When we do that simple test, we find that a highly statistically 
significant excess of pairs share a branch of the tree, much more 
than we expect by chance."

It is a surprising result, since there are plenty of reasons why 
people might have the same surname but be unrelated: many names were 
founded by more than one man, for example. There is also the issue 
of illegitimacy. The researchers predicted that more than 1% of 
children were illegitimate in each generation. Over many 
generations, this could have built up a significant error.

"Those two elements would act as a strong force to break any links," 
said Dr Jobling. "It was a surprise that by choosing just pairs we 
got a clear signal of sharing ancestors."


http://www.guardian.co.uk/crime/article/0,,1715022,00.html




-- 
School of Computing Science, University of Newcastle, Newcastle upon Tyne,
NE1 7RU, UK
EMAIL = Brian.Randell () ncl ac uk   PHONE = +44 191 222 7923
FAX = +44 191 222 8232  URL = http://www.cs.ncl.ac.uk/~brian.randell/

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